Discorsi e Dimostrazioni Matematiche, Intorno a Due Nuoue Scienze attenenti alla mecanica & movimenti locali …. Leiden: Elzevir, 1638
First edition, the rare first issue, of the Two New Sciences, Galileo’s greatest work. Galileo’s “Mathematical Discourses and Demonstrations … is now considered by most scientists as Galileo’s greatest work. … It was upon his foundations that Huygens, Newton and others were able to erect the frame of the science of dynamics, and to extend its range (with the concept of universal gravitation) to the heavenly bodies” (PMM).
The Origin of Species by Means of Natural Selection, or the preservation of favoured races in the struggle for life. Sixth edition, with additions and corrections. (Eleventh thousand.). London: John Murray, 1872
Sixth and final edition, first issue. A splendid and rare presentation copy inscribed by Darwin on the half-title: “From the author with best regards.”
WATSON, JAMES D. & FRANCIS CRICK
“Molecular structure of nucleic acids. A structure of deoxyribose nucleic acid.” Offprint from: Nature Vol. 171 (April 25, 1953). London, 1953
FIRST EDITION, THE RARE OFFPRINT. Signed by Watson and Crick. This volume is also inscribed and signed by Maurice Wilkins and Alec R. Stokes, co-authors of the second paper with H R. Wilson. Wilkins shared the 1962 Nobel Prize in Medicine with Watson and Crick.
VON NEUMANN ,JOHN, ET AL
Ergebnisse eines mathematischen Kolloquiums, unter Mitwirkung Kurt Gödel und George Nobeling. Herausgegen von Kurt Menger. Heft 1-8.. Leipzig & Berlin: B. G. Teubner and F. Deuticke, [1931-1937].
A rare complete run of first editions of the proceedings of the celebrated Vienna Colloquium.
Iconic signed Darwin photograph “I like this photograph much better than any other which has been taken of me.”(DARWIN, CHARLES.) CAMERON, JULIA MARGARET
Portrait of Charles Darwin, signed by Darwin and by Cameron. Cameron, 
THE ICONIC PORTRAIT OF CHARLES DARWIN, boldly signed by Charles Darwin and by Julia Margaret Cameron.
“Eine neue Bestimmung der Molekueldimensionen” (pp. 289-306) and “Zur Theorie der Brownschen Bewegung” (pp. 371-381) in Annalen der Physik 4th series, vol. 19, no. 2.. Leipzig, 1906
First journal edition of Einstein’s doctoral thesis, revised, and first edition of his second paper on Brownian motion. Signed and dated 1950 by Einstein on p. 289 at the beginning of his thesis.
WATSON, JAMES D. & Andrew Berry
DNA The Secret of Life. [New York: Knopf, 2003.]
Presentation copy inscribed by James Watson to Francis Crick and his wife: “For Francis and Odile from Jim 27 November 2002.” This is the dedication copy, with the printed dedication stating “To Francis Crick.”
two items: $45,000
VON BRAUN, WERNHER
Original drawing, “3-Stage Satellite Vehicle (pitch plane)” signed and dated 1952. [Huntsville, Alabama, 1952.]
his is an original signed drawing of a space ship by Wernher von Braun, the father of the American space program. He made this drawing for his landmark Colliers series “Man Will Conquer Space Soon” (1952-54), which played a central role in inspiring a generation of rocket scientists and convincing the public of the possibility of space exploration. These essays covered seemingly every aspect of manned space flight and anticipated many developments including the enormous multi-stage vertical launch vehicle (to become Saturn V), a horizontal landing space ferry (the Space Shuttle), an orbiting space station, a lunar landing, the establishment of a base on the moon, and ultimately a manned expedition to Mars.
GODDARD, ROBERT H
Autograph manuscript diagrams and text. [n.p., n.d.],
Goddard (1882-1945), the “father of modern rocket propulsion,” launched the world’s first liquid-propellant rocket on March 16, 1926, at Auburn, Massachusetts, a “feat as epochal in history as that of the Wright brothers at Kitty Hawk” (NASA). Goddard had a rare genius for invention and these notes suggest the endless refinement necessary to create a dependable, operational rocket engine.
Experiments and Observations in Soaring Flight. Offprint from: Journal of the Western Society of Engineers 8 [misprinted “III” on front wrapper], no. 4 (August, 1903). [Chicago], 
FIRST EDITION, offprint issue. Presentation copy with the stamp of the Wrights’ advisor, mentor, and chief promoter, aviation pioneer Octave Chanute. Chanute was the most important figure in aviation from 1890 to 1910